Workers exposed to chlorine agents have been diagnosed with respiratory impairments. A recent study has reported that "suggest that bleach inhalation at a concentration of 0.4 ppm—a concentration below 8-hr permissible occupational exposure level—brings about a substantial decrease in FEV1 in subjects."
"Included in the study were thirteen cleaning employees with work-related asthma-like symptoms, three asthmatic controls and three atopic subjects without bronchial hyperresponsiveness (BHR) who had no exposure to cleaning products. The study protocol consisted of a methacholine test, sputum induction and fraction of exhaled nitric oxide measurement (FENO) both at baseline and 24 hr after a 1-hr inhalation challenge with either placebo or bleach at a concentration of 0.4 ppm of chlorine."
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