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When other disorders exist, i.e., renal calculi, renal failure, these disorders may be combined with the above impairments.
A patient with hypothalamic-pituitary disease belongs in Class 3 when severe symptoms and signs persist despite treatment. When appropriate, other impairments, i.e., neurologic or visual impairments, may be combined with the above impairments.

THYROID STRUCTURE OR FUNCTION
Class 1. Impairment of the Whole Person, 1—10%
A patient belongs in Class 1 when
(a) continuous thyroid therapy is required for correction of the thyroid insufficiency or for maintenance of normal thyroid anatomy; and
(b) there is no objective physical or laboratory evidence of Inadequate replacement therapy.

Class 2. Impairment of the Whole Person, 11—20%
A patient belongs in Class 2 when
(a) symptoms and signs of thyroid disease are present or there is anatomic loss or alteration; and
(b) continuous thyroid hormone replacement therapy is required for correction of the confirmed thyroid insufficiency; but
(c) the presence of a disease process in another body system or systems permits only partial replacement of the thyroid hormone.
May combine with other disorders where appropriate, i.e., cardiovascular disease.

PARATHYROID STRUCTURE OR FUNCTION
Severity of Hyperparathyroidism % Impairment of the Whole Person
Symptoms and signs are easily controlled with medical therapy 1—10
There is persistent mild hypercalcemia with a mild nausea and polyuria 11—20
There is severe hypercalcemia with nausea and lethargy 21—90

Hypoparathyroidism is a chronic condition of variable severity that requires long term medical therapy in most cases. The degree of severity determines the degree of permanent impairment according to the following:

Severity of Hypoparathyroidism % Impairment of the Whole Person
Symptoms and signs easily controlled by medical therapy 1—5
Intermittent hypercalcemia and/or hypocalcemia and more frequent symptoms in spite of careful medical attention 6—20

When other disorders exist, i.e., renal calculi, renal failure, these disorders may be combined with the above impairments.


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